2025
Karamertzanis PG, Rasenberg M, Shah I, Patlewicz G . 2025. Modelling in vitro mutagenicity using multi-task deep learning and REACH data. Chem Res Toxicol 38(8):1382-1407; doi: 19.1021/acs.chemrestox.5c00152 . PMID: 40680271.
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Topics: modeling , regulatory toxicology
Clouser MC, Suh M , Movva N, Hildebrand JS, Pastula ST, Schoehl M, Hindoyan A, Balasubramanian A, et al. 2025. A systematic literature review of MTAP deletions in solid and hematologic cancers. Cancer Treat Res Comm 44:100966; doi: 10.1016/j.ctarc.2025.100966 . PMID: 40729867.
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Topics: Cancer , Systematic Review
Patlewicz G , Judson, Paul Friedman K, Wetmore BA, DeVito MJ, Harrill JA, Carstens KE, Houck KA, et al. 2025. Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs). J Toxicol Environ Health B online ahead of print July 6; doi: 10.1080/10937404.2025.2521615 . PMID: 40619890.
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Topics: NAMs , PFAS
Kenyon EM, DeVito MJ, Patlewicz G , Adams LD, Thomas RS, Ambroso JL, Yang X, Blake JC, et al. 2025. Subchronic toxicity of four per- and polyfluoroalkyl substances by oral exposure in Sprague Dawley rats. Toxics 13(7):524; doi: 10.3390/toxics13070524 . PMID: 40710969.
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Topics: PFAS
Leary A, Shah I, Patlewicz G . 2025. An exploration of the use of hybrid fingerprints in Generalized Read-Across and their impact on predictive performance for selected in vivo toxicity outcomes. Comput Toxicol 34(June):100349; doi: 10.1016/j.comtox.2025.100349 .
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Topics: NAMs , read-across
Hagan B, Shah I, Patlewicz G . 2025. Can graph similarity metrics be helpful for analogue identification as part of a read-across approach? Comput Toxicol 34(June):100353; doi: 10.1016/j.comtox.2025.100353 .
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Hughes MF, DeVito MJ, Patlewicz G , Thomas RS, Adams LD, Ambroso JL, Yang X, Upadhyay BG, et al. 2025. Immunotoxicity of four per- and polyfluoroalkyl substances following 28-day oral repeat dosing in rats assessed by the anti-sheep red blood IgM response. Toxics 13(6):490; doi: 10.3390/toxics13060490 . PMID: 40559963.
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Topics: PFAS
Brorby G, Franzen A, Thompson C, Wikoff D , Doepker C. 2025. Human health risk assessment of three smoke flavoring primary products. Food Chem Toxicol 202(Aug):115490; doi: 10.1016/j.fct.2025.115490 . PMID: 40320068.
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Topics: food safety , Food science , genotoxicity , risk assessment , safety assessment
Hagan B, Groff L, Patlewicz G , Shah. 2025. Toward metabolic similarity in read-across: A case study using graph convolutional networks to predict genotoxicity outcomes. Chem Res Toxicol 38(6):1122-1133; doi: 10.1021/acs.chemrestox.5c00120 . PMID: 40432291.
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Topics: genotoxicity
Diemar MG, Giusti A, Michel-Caillet C, Leme DM, Wikoff D , Bloch D, Sass J, Beekmann K, et al. 2025. How to organize a successful toxicology workshop? A participant perspective on the Collaboration to Harmonise the Assessment of Next Generation Evidence (CHANGE) workshop in Oslo, 18-20 June 2024. Arch Toxicol 99(7):3057-3063 ; doi : 10.1007/s00204-025-04064-6 . PMID: 40372420.
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