2025
Borghoff SJ , Rivera BN, Fitch S , Buerger A, Choksi N, Franzen A , Bus J, Rushton EK, Lea I . Systematic evaluation of the evidence base on methyl tert-butyl ether for carcinogenic potential in humans; Low concern based on animal cancer studies and mechanistic data. Abstract 4702, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: carcinogens , MTBE
Wikoff D . Use cases of strategic application of ML/AI in the risk assessment process. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Topics: Food science , risk assessment
Wikoff D . Pragmatic solutions for better using evidence-based methods to integrate observational data in food safety assessments. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Topics: Food science , risk assessment
2024
Suh M, Mittal L, Brorby G , Pastula S, Vincent M, Proctor D. Epidemiology is critical in advancing cumulative impact assessment (CIA) research: A pilot study in San Antonio, Texas. International Society of Exposure Science, Montreal, Canada, October 2024.
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Topics: Air Quality , Epidemiology
East A, Klaren W , Covington T, Rish W. Exploring biomarker-based methods to incorporate non-chemical stressor exposures into cumulative assessments for potentially vulnerable population groups. International Society of Exposure Science, Montreal, Canada, October 2024.
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Topics: Air Quality , Epidemiology
Cook B, Nelms MD, Harris D, Bever RJ, Lynn SC, Borghoff S , et al. Clustering chemicals for predicting behavior and hazards: Insights from the endocrine disruptor screening program (EDSP) universe of chemicals. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: Epidemiology , mode of action
Reátegui-Zirena EG, Lange SS, Jenkins A, Heintz MM, Franke K, Perry CS, Thompson C , et al. Acute health-based screening level derivation for cyanotoxins (microcystin, cylindrospermopsin and anatoxins). Abstract 7.05P-Th-197, Society of Environmental Toxicology and Chemistry, 45th Annual Meeting, Fort Worth, TX, October 2024.
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Topics: ecotoxicology , water
Covington TR, Borghoff SJ , Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: modeling
Lea IA , Borghoff SJ, Chew R, Bell S, Edwards S, Vasko J, et al. Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: Systematic Review
Holt JR, Chew RF, Bunnage E, Lea I, Borghoff SJ, Sayer R, et al. Categorizing articles for environmental health systematic evidence mapping: A zero-shot machine learning approach using large language models. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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