2023
Rogers JM, Heintz MM, Thompson CM, Haws LC. 2023. A putative adverse outcome network for neonatal mortality and lower birth weight in rodents: Applicability to per- and polyfluoroalkyl substances and relevance to human health. Birth Defects Res 115(11)1011-1062; doi: 10.1002/bdr2.2185 . PMID: 37219003.
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Topics: Exposure Assessment , PFAS , Toxicology
Meek ME, Wikoff D . 2023. The need for good practice in the application of mechanistic constructs in hazard and risk assessment. Toxicol Sci 194(1):13-22; doi: 10.1093/toxsci/kfad039 . PMID: 3707944.
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Topics: risk assessment , Toxicology
Thompson CM , Heintz MM , Wolf JC, Cheru R, Haws LC, Cullen JM. 2023. Assessment of mouse liver histopathology following exposure to HFPO-DA with emphasis on understanding mechanisms of hepatocellular death. Toxicol Pathol 51(1–2):4–14; doi: 10.1177/01926233231159078 . PMID: 36987989.
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Topics: Exposure Assessment , Toxicology
Heintz MM , Haws LC, Klaunig JE, Cullen JM, Thompson CM . 2023. Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans. Toxicol Sci 192(1):15–29; doi: 10.1093/toxic/kfad004 . PMID: 36629480.
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Topics: Cancer , Toxicology
Thompson CM , Proctor DM, Harris MA. 2023. Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data.” Environ Mol Mutagen 64(4):259–260; doi: 10.1002/em.22537 . PMID: 36916184.
Topics: Hexavalent Chromium , Toxicology
Borghoff SJ , Cohen SS, Jiang X, Lea IA , Klaren WD , Chappell GA, Britt JK , Rivera BN, Choksi NY, Wikoff DS . 2023. Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame. Food Chem Toxicol 172(Feb):113549; doi: 10.1016/j.fct.2022.113549 .
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Topics: Systematic Review , Toxicology
Borghoff SJ , Cohen SS, Jiang X, Lea IA , Klaren WD , Chappell GA, Britt JK , Rivera BN, Choksi NY, Wikoff DS . 2023. Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame. Food Chem Toxicol 172(Feb):113549; doi: 10.1016/j.fct.2022.113549 . PMID: 36493943.
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