2022
Richard AM, Hidle H, Patlewicz G , Williams AJ. 2022. Identification of branched and linear forms of PFOA and potential precursors: A user-friendly SMILES structure-based approach. Front Environ Sci 10(Mar 24):865488; doi: 10.3389/fenvs.2022.865488 . PMID: 35494535.
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Topics: PFAS
Hoffmann S, Aiassa E, Angrish M, Beausoleil C, Bois FY… Wikoff D , et al. 2022. Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks. ALTEX 39(3):499-518; doi: 10.14573/altex.2202141 . PMID: 35258090.
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Topics: chemical safety assessment , evidence-based reviews
Chappell GA, Wolf JC, Thompson CM . 2021. Crypt and villus transcriptomic responses in mouse small intestine following oral exposure to hexavalent chromium. Toxicol Sci 186(1):43-57; doi: 10.1093/toxsci/kfab152 . PMID: 34935971.
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Topics: chromium , transcriptomics
Boyce M, Meyer B, Grulke C, Lizarraga L, Patlewicz G . 2022. Comparing the performance and coverage of selected in silico (liver) metabolism tools related to reported studies in the literature to inform analogue selection in read-across: A case study. Comput Toxicol 21(Feb):100208; doi: 10.1016/j.comtox.2021.100208 . PMID: 35386221.
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Topics: NAMs
Beal MA, Gagne M, Kulkarni SA, Patlewicz G , Thomas RS, Barton-Maclaren TS. 2022. Implementing in vitro bioactivity to modernize priority setting of chemical inventories. ALTEX 39(1):123-139; doi: 10.14573/altex.2106171 . PMID: 34818430.
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Topics: NAMs , toxicokinetics
2021
Wang Z, Buser A, Cousins I, Demattio S, Drost W, Johansson O, Ohno K, Patlewicz G , et al. 2021. A new OECD definition for per- and polyfluoroalkyl substances. Environ Sci Technol 55(23):15575-15578; doi: 10.1021/acs.est.1c06896 . PMID: 34751569.
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Topics: PFAS
Tice RR, Bassan A, Amberg A, Anger LT, Beal MA, Bellion P, Benigni R, Birmingham J…, Mihalchik-Burhans AL , et al. 2021. In silico approaches in carcinogenicity hazard assessment: Current status and future needs. Comp Toxicol 20(Nov):100191; doi: 10.1016/j.comtox.2021.100191 . PMID: 35368437.
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Topics: Cancer , carcinogens
Thompson CM , Aardema MJ, Heintz MM , MacGregor JT, Young RR. 2021. A review of mammalian in vivo genotoxicity of hexavalent chromium: Implications for oral carcinogenicity risk assessment. Crit Rev Toxicol 51(10)820-849; doi: 10.1080/10408444.2021.2000934 . PMID: 35060824.
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Topics: carcinogens , chromium , genotoxicity
Black MB, Andersen ME, Pendse SN, Borghoff SJ , Streicker M, McMullen PD. 2021. RNA-sequencing (transcriptomic) data collected in liver and lung of male and female B6C3F1 mice exposed to various dose levels of 4-methylimidazole for 2, 5, or 28 days. Data in Brief 38(Oct):107420; doi: 10.1016/j.dib.2021.107420 . PMID: 34660856.
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Topics: transcriptomics
Palermo CM, Foreman JE, Wikoff DS , Lea I . 2021. Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development. Curr Res Toxicol 2(July 22):254–271; doi: 10.1016/j.crtox.2021.07.002 . PMID: 34401750.
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