2025
Heintz MM, Buerger AN, Haws LC, East AW , Cullen JM, Thompson CM . Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and PPARα knockout mice. Abstract 3972, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025
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Topics: PFAS , Toxicology
Fitch S, Wikoff D , Foreman J, Buerger A, Haws L, Palmero C. Assessment of relative potency factors for six phthalates. Abstract 4235, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: phthalates , Toxicology
Cook B, Nelms M, Harris D, Bever RJ, Lynn SG, Williams D, Borghoff S , Edwards SW, Markey K. Identifying structural overlap between EDSP universe of chemicals and ToxCast/Tox21 using chemical clustering and uniform manifold approximation and projection. Abstract 4034, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: Toxicology
Buerger AN, Vincent MJ, Fitch S , Rushton EK, Borghoff SJ . Evaluation of potential obesogenicity through a mode of action approach: A case study with MTBE. Abstract 3928, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: MTBE
Borghoff SJ, Rivera BN, Fitch S, Buerger A, Choksi N, Franzen A , Bus J, Rushton EK, Lea I . Systematic evaluation of the evidence base on methyl tert-butyl ether for carcinogenic potential in humans; Low concern based on animal cancer studies and mechanistic data. Abstract 4702, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: carcinogens , MTBE
2024
Suh M, Mittal L, Brorby G , Pastula S, Vincent M, Proctor D. Epidemiology is critical in advancing cumulative impact assessment (CIA) research: A pilot study in San Antonio, Texas. International Society of Exposure Science, Montreal, Canada, October 2024.
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Topics: Air Quality , Epidemiology
East A, Klaren W , Covington T, Rish W. Exploring biomarker-based methods to incorporate non-chemical stressor exposures into cumulative assessments for potentially vulnerable population groups. International Society of Exposure Science, Montreal, Canada, October 2024.
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Topics: Air Quality , Epidemiology
Cook B, Nelms MD, Harris D, Bever RJ, Lynn SC, Borghoff S , et al. Clustering chemicals for predicting behavior and hazards: Insights from the endocrine disruptor screening program (EDSP) universe of chemicals. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: Epidemiology , Toxicology
Covington TR, Borghoff SJ , Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: modeling
Lea IA , Borghoff SJ, Chew R, Bell S, Edwards S, Vasko J, et al. Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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