2008
Subramaniam RP, Chen C, Crump KS, Devoney D, Fox JF, Portier CJ, Schlosser PM, Thompson CM , White P. 2008. Uncertainties in biologically-based modeling of formaldehyde-induced respiratory cancer risk: Identification of key issues. Risk Anal 28(4):907–923; doi: 10.1111/j.1539-6924.2008.01083.x . PMID: 18564991.
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Topics: Cancer , Exposure Assessment , formaldehyde , risk assessment
Thompson CM , Sonawane B, Barton HA, DeWoskin RS, Schlosser P, Lipscomb JC, Chiu W, Krishnan K. 2008. Approaches for applications of physiologically based pharmacokinetic models in risk assessment. J Toxicol Environ Health B 11(7):519–547; doi: 10.1080/10937400701724337 . PMID: 18584453.
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Topics: modeling , PBPK/PBDE , pharmacokinetics , risk assessment
DeWoskin RS, Thompson CM. 2008. Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants. Regul Toxicol Pharmacol 51(June):66–86; doi: 10.1016/j.yrtph.2008.02.005 . PMID: 18433959.
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Topics: modeling , PBPK/PBDE
Richardson VM, Staskal DF , Ross DG, Diliberto JJ, Devito MJ, Birnbaum LS. 2008. Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener. Toxicol Appl Pharmacol 226(3):244-250; doi: 10.1016/j.taap.2007.09.015 . PMID: 17964624.
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Topics: flame retardants , PBPK/PBDE
2007
Lea IA , Jackson MA, Li X, Bailey S, Peddada SD, Dunnick JK. 2007. Genetic pathways and mutation profiles of human cancers: Site- and exposure-specific patterns. Carcinogenesis 28(9):1851–1858; doi: 10.1093/carcin/bgm176 . PMID: 17693665.
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Topics: Cancer
Simon T, Britt JK, James RC. 2007. Development of a neurotoxic equivalence scheme of relative potency for assessing the risk of PCB mixtures. Regul Toxicol Pharmacol 48(2):148-170; doi: 10.1016/j.yrtph.2007.03.005 . PMID: 17475378.
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Topics: PCBs
Liebelt EL, Balk SJ, Faber W, Fisher JW, Hughes CL, Lanzkron SM, Lewis KM, Marchetti F, Mehendale HM, Rogers JM , Shad AT, Skalko RG, Stanek EJ. 2007. NTP-CEHR expert panel report on the reproductive and developmental toxicity of hydroxyurea. Birth Defects Res B 80(4):259–366; doi: 10.1002/bdrb.20123 . PMID: 17712860.
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Topics: chemical safety assessment , reproductive toxicology
Urban JD , Clarke WP, von Zastrow M, Kobilka B, Nichols DE, Weinstein H, Javitch JA, Roth BL, et al. 2007. Functional selectivity and classical concepts of quantitative pharmacology. J Pharmacol Exp Therap 320(1):1-13; doi: 10.1124/jpet.106.104463 . PMID: 16803859.
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Topics: pharmacology
Thompson CM , Grafström RC. 2007. Mechanistic considerations for formaldehyde-induced bronchoconstriction involving S-nitrosoglutathione reductase. J Toxicol Environ Health A 71(3):244–248; doi: 10.1080/15287390701598259 ; PMID: 18097950.
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Topics: formaldehyde
Urban JD , Vargas G, von Zastrow M, Mailman RB. 2007. Aripiprazole has functionally selective actions at D2 receptor-mediated signaling pathways. Neuropsychopharmacol 32(1):67-77; doi: 10.1038/sj.npp.1301071 . PMID: 16554739.
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