Jonathan D. Urban, Ph.D., DABT
Managing Scientist, Associate Practice Director, Health Sciences


Phone(512) 351-7358
Fax(512) 382-6945
LocationAustin, TX
Address9390 Research Blvd
Suite 100
Austin, Texas 78759



Professional Profile

Dr. Jonathan Urban is a Managing Scientist with the Center for 21st Century Toxicology, in Austin, Texas.

Dr. Urban is a board-certified toxicologist with more than ten years’ experience studying and evaluating the potential health effects of a wide range of chemicals of concern (e.g., halogenated aromatic hydrocarbons, solvents, pesticides, metals, hazardous air pollutants), food-related compounds, and consumer product ingredients and contaminants. He is currently supporting the firm’s efforts developing and applying systematic review methods to the chemical risk assessment process. Specifically, Dr. Urban is experienced in developing problem formulation and PECO questions, literature identification and screening protocols (search strategies, inclusion and exclusion criteria), application of critical appraisal tools for evaluating individual studies for internal (i.e., risk of bias) and external validity, and qualitative and quantitative evidence integration. Dr. Urban has used this expertise in the development of critiques and recommendations regarding risk-based toxicity criteria for regulatory agencies, industry, and private-sector businesses. In addition to chemical toxicology evaluations, he specializes in conducting human health risk assessments, federal and state site remediation investigations, and biomonitoring studies. He also develops and provides oversight for GLP and non-GLP studies in support of the FDA’s pre-IND application process for biological pharmaceuticals, including CRO site study monitoring of non-clinical studies. Furthermore, Dr. Urban has considerable experience managing and providing technical and logistical assistance on tobacco-product toxicology and risk assessment projects in support of the Center for Tobacco Products (FDA).

Dr. Urban earned a Ph.D. in toxicology at the University of North Carolina at Chapel Hill, where he developed and advanced various in vitro assays for studying receptor-based signaling pathways associated with cellular G-protein coupled receptor (GPCG) activation in neurological models. He is a Diplomate of the American Board of Toxicology, is a member of the Scientific Review Panel for the National Library of Medicine’s Hazardous Substance Databank, has published academic and professional studies in the peer-reviewed literature, and is a reviewer for various scientific journals. While in graduate school, Dr. Urban also served as an enlisted communications specialist in the United States Marine Corps Reserves (Communications Company, Greensboro, NC).